Publications

Featured Publications

Allele-specific gene editing rescues pathology in a human model of Charcot-Marie-Tooth disease type 2E. Feliciano CM, Wu K, Watry HL, Marley CBE, Ramadoss GN, Ghanim HY, Liu AZ, Zholudeva LV, McDevitt TC, Saporta MA, Conklin BR, Judge LM. (2021) Front. Cell Dev. Biol., Aug 16; 9:723023. PMID: 34485306, PMCID: PMC8415563

CRISPR interference efficiently induces specific and reversible gene silencing inhuman iPSCs. Mandegar MA, Huebsch N, Frolov EB, Shin E, Truong A, Olvera MP, Chan AH, Miyaoka Y, Holmes K, Spencer CI, Judge LM, Gordon DE, Eskildsen TV, Villalta JE, Horlbeck MA, Gilbert LA, Krogan NJ, Sheikh SP, Weissman JS, Qi LS, So P-L, Conklin BR. (2016) Cell Stem Cell., Apr 7; 18(4)541–553. PMID: 26971820, PMCID: PMC4830697

Isolation of single-base genome-edited human iPS cells without antibiotic selection. Miyaoka Y, Chan AH, Judge LM, Yoo J, Huang M, Nguyen TD, Lizarraga PP, So PL, Conklin BR. (2014) Nat. Methods, Mar; 11(3):291–293.PMID: 24509632, PMCID: PMC4063274

Engineering GPCR signaling pathways with RASSLs. Conklin BR, Hsiao EC, Claeysen S, Dumuis A, Srinivasan S, Forsayeth JR, Guettier J-M, Chang WC, Pei Y, McCarthy KD, Nissenson RA, Wess J, Bockaert J, Roth BL. (2008) Nat. Methods, Aug; 5(8):673–678. PMID: 18668035, PMCID: PMC2703467